BDBM298383 N-(5-(tert-Butyl)-3-(3-(4-((2-((3-cyano-4-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)phenyl) amino)pyridin-4-yl)oxy)naphthalen-1-yl)ureido)-2-methoxyphenyl)methanesulfonamide::US10125100, Example 8::US10392346, Example 8::US10941115, Example 8::US9751837, Example 8

SMILES COCCOCCOCCOc1ccc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc1C#N

InChI Key InChIKey=WGFQWNGYIXQPPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298383   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Topivert Pharma

US Patent
LigandPNGBDBM298383(N-(5-(tert-Butyl)-3-(3-(4-((2-((3-cyano-4-(2-(2-(2...)
Affinity DataIC50:  3.77E+3nMAssay Description:GSK 3α Method 2: This method follows the same steps as Method 1, but utilises a shorter period of mixing of the test compound (105 minutes inste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBaculoviral IAP repeat-containing protein 2 [174-256](Homo sapiens (Human))
Topivert Pharma

US Patent
LigandPNGBDBM298383(N-(5-(tert-Butyl)-3-(3-(4-((2-((3-cyano-4-(2-(2-(2...)
Affinity DataIC50:  214nMAssay Description:p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent