BDBM29925 substituted 6-aminoquinoline-3-carbonitrile, 36

SMILES CC(C)N1CCC(CC1)n1cc(CNc2cc(Cl)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)nn1

InChI Key InChIKey=GBYSPHCOZHPPFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29925   

LigandPNGBDBM29925(substituted 6-aminoquinoline-3-carbonitrile, 36)
Affinity DataIC50:  9.10nMAssay Description:Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues 217 and 221 of GST-MEK1 was detected by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed