BDBM300659 6-(4-fluorophenyl)-N-{4- methoxy-3-[(morpholin-4- ylacetyl)amino]phenyl} nicotinamide::US10130633, Example 229

SMILES COc1ccc(NC(=O)c2ccc(nc2)-c2ccc(F)cc2)cc1NC(=O)CN1CCOCC1

InChI Key InChIKey=BHVKNAHHCBACKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300659   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300659(6-(4-fluorophenyl)-N-{4- methoxy-3-[(morpholin-4- ...)
Affinity DataIC50: >5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300659(6-(4-fluorophenyl)-N-{4- methoxy-3-[(morpholin-4- ...)
Affinity DataIC50:  2.30E+3nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent