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BDBM300762 US10130642, Example 8-2

SMILES: CC(CO)(CC(Cc1ccc(cc1)-c1ccccc1F)NC(=O)c1cnn[nH]1)C(O)=O

InChI Key: InChIKey=BOAUMKBGSVYOEB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300762   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Homo sapiens (Human))
BDBM300762
PNG
(US10130642, Example 8-2)
Show SMILES CC(CO)(CC(Cc1ccc(cc1)-c1ccccc1F)NC(=O)c1cnn[nH]1)C(O)=O
Show InChI InChI=1S/C22H23FN4O4/c1-22(13-28,21(30)31)11-16(25-20(29)19-12-24-27-26-19)10-14-6-8-15(9-7-14)17-4-2-3-5-18(17)23/h2-9,12,16,28H,10-11,13H2,1H3,(H,25,29)(H,30,31)(H,24,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<1n/an/an/an/an/an/an/an/a



THERAVANCE BIOPHARMA R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...


US Patent US10130642 (2018)

More data for this
Ligand-Target Pair