BDBM300846 (3S)-3-(4-((3-(2-Methyl-6- (methylsulfonamido)phenyl) benzo[b]thiophen-5- yl)methoxy)phenyl) hex-4-ynoic acid::US10131648, Compound 44::US10195178, Compound 44::US9790198, Compound 44

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3scc(-c4c(C)cccc4NS(C)(=O)=O)c3c2)cc1

InChI Key InChIKey=BRCIOIJRMGUBHA-QFIPXVFZSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300846   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300846((3S)-3-(4-((3-(2-Methyl-6- (methylsulfonamido)phen...)
Affinity DataEC50:  22nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300846((3S)-3-(4-((3-(2-Methyl-6- (methylsulfonamido)phen...)
Affinity DataEC50:  22nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300846((3S)-3-(4-((3-(2-Methyl-6- (methylsulfonamido)phen...)
Affinity DataEC50:  22nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent