BDBM300851 (3S)-3-(4-((3-(5-(2- Methoxyethoxy)-2- methylpyridin-3- yl)benzo[b]thiophen-5- yl)methoxy)phenyl) hex-4-ynoic acid::US10131648, Compound 49::US10195178, Compound 49::US9790198, Compound 49

SMILES COCCOc1cnc(C)c(c1)-c1csc2ccc(COc3ccc(cc3)[C@H](CC(O)=O)C#CC)cc12

InChI Key InChIKey=OJOJSIHEEMLRKU-QHCPKHFHSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300851   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300851((3S)-3-(4-((3-(5-(2- Methoxyethoxy)-2- methylpyrid...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300851((3S)-3-(4-((3-(5-(2- Methoxyethoxy)-2- methylpyrid...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300851((3S)-3-(4-((3-(5-(2- Methoxyethoxy)-2- methylpyrid...)
Affinity DataEC50:  9nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent