BDBM300861 (3S)-3-{4-[((3-{4-[(1,1-Dioxo- tetrahydro-2H-thiopyran-4- yl)methoxy]-2-methylphenyl}- 1-benzothiophen-5- yl)oxy)methyl]phenyl} hex-4-ynoic acid::US10131648, Compound 59::US10195178, Compound 59::US9790198, Compound 59

SMILES CC#C[C@@H](CC(O)=O)c1ccc(COc2ccc3scc(-c4ccc(OCC5CCS(=O)(=O)CC5)cc4C)c3c2)cc1

InChI Key InChIKey=WTRSCKQZMRYDAZ-MHZLTWQESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300861   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300861((3S)-3-{4-[((3-{4-[(1,1-Dioxo- tetrahydro-2H-thiop...)
Affinity DataEC50:  14nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300861((3S)-3-{4-[((3-{4-[(1,1-Dioxo- tetrahydro-2H-thiop...)
Affinity DataEC50:  14nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300861((3S)-3-{4-[((3-{4-[(1,1-Dioxo- tetrahydro-2H-thiop...)
Affinity DataEC50:  14nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent