BDBM301040 (+-)-4-[5-(4-methylphenyl)-2- [(morpholin-2- ylmethyl)amino]pyrimidin-4- yl]benzonitrile::US10131664, Example 33::US10543198, Example 33::US10864202, Example 33

SMILES Cc1ccc(cc1)-c1cnc(NCC2CNCCO2)nc1-c1ccc(cc1)C#N

InChI Key InChIKey=SWFYDUBBUMYNOJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 301040   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301040((+-)-4-[5-(4-methylphenyl)-2- [(morpholin-2- ylmet...)
Affinity DataIC50: <10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301040((+-)-4-[5-(4-methylphenyl)-2- [(morpholin-2- ylmet...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301040((+-)-4-[5-(4-methylphenyl)-2- [(morpholin-2- ylmet...)
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent