BDBM301048 4-[5-(4-methylphenyl)-2-{9-oxa-3,7- diazabicyclo[3.3.1]nonan-3- yl}pyrimidin-4-yl]benzonitrile::US10131664, Example 41::US10543198, Example 41::US10864202, Example 41

SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CC2CNCC(C1)O2

InChI Key InChIKey=ZFSRDDRPHFBTBE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 301048   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301048(4-[5-(4-methylphenyl)-2-{9-oxa-3,7- diazabicyclo[3...)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301048(4-[5-(4-methylphenyl)-2-{9-oxa-3,7- diazabicyclo[3...)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301048(4-[5-(4-methylphenyl)-2-{9-oxa-3,7- diazabicyclo[3...)
Affinity DataIC50:  550nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent