BDBM301104 4-[2-(4-aminopiperidin-1-yl)-5-[2-(4- hydroxyoxan-4-yl)ethynyl]pyrimidin- 4-yl]-2-fluorobenzonitrile::US10131664, Example 97
SMILES NC1CCN(CC1)c1ncc(C#CC2(O)CCOCC2)c(n1)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=BYNCKDGTVULUEE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 301104
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair