BDBM301109 4-[2-(4-aminopiperidin-1-yl)-5-[2-(1- methylpyrazol-4-yl)ethynyl]pyrimidin- 4-yl]-2-fluorobenzonitrile::US10131664, Example 102
SMILES Cn1cc(cn1)C#Cc1cnc(nc1-c1ccc(C#N)c(F)c1)N1CCC(N)CC1
InChI Key InChIKey=GWXHLOVFMNBJNE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 301109
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair