BDBM301160 4-[2-(4-aminopiperidin-1-yl)-6- methoxy-5-[1-(2,2,2-trifluoroethyl)- 1H-pyrazol-4-yl]pyrimidin-4- yl]benzonitrile::US10131664, Example 153
SMILES COc1nc(nc(-c2ccc(cc2)C#N)c1-c1cnn(CC(F)(F)F)c1)N1CCC(N)CC1
InChI Key InChIKey=GPQZFJGNKQXZBT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 301160
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair