BDBM301161 4-[2-(4-aminopiperidin-1-yl)-6- methoxy-5-(1-methyl-1H-1,2,3- benzotriazol-5-yl)pyrimidin-4- yl]benzonitrile::US10131664, Example 154

SMILES COc1nc(nc(-c2ccc(cc2)C#N)c1-c1ccc2n(C)nnc2c1)N1CCC(N)CC1

InChI Key InChIKey=NSWHTZOCFFAPJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301161   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM301161(4-[2-(4-aminopiperidin-1-yl)-6- methoxy-5-(1-methy...)
Affinity DataIC50: <10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent