BDBM301792 N-(4-(4-(3-Cyano-5-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide::US9598387, Compound 4::US9969743, 4

SMILES FC(F)(F)c1cc(cc(c1)N1CCN(CCCCNC(=O)N2CCN(CC2)c2ccccc2)CC1)C#N

InChI Key InChIKey=KUNJWDFGNSXWFX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 301792   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301792(N-(4-(4-(3-Cyano-5-(trifluoromethyl)phenyl)piperaz...)
Affinity DataKi:  4.10nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301792(N-(4-(4-(3-Cyano-5-(trifluoromethyl)phenyl)piperaz...)
Affinity DataKi:  4.10nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301792(N-(4-(4-(3-Cyano-5-(trifluoromethyl)phenyl)piperaz...)
Affinity DataKi:  294nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Southern Research Institute

US Patent
LigandPNGBDBM301792(N-(4-(4-(3-Cyano-5-(trifluoromethyl)phenyl)piperaz...)
Affinity DataKi:  294nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent