BDBM302393 4-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbonyl}piperazin-2-one::US9598416, Example 39

SMILES COc1cc(C)cc2cc(sc12)-c1c(cn2ncnc(N)c12)C(=O)N1CCNC(=O)C1

InChI Key InChIKey=HYOBLDWQELJNSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302393   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM302393(4-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...)
Affinity DataIC50:  51.7nMAssay Description:Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent