BDBM302674 2-(4-Fluoro-3- methylphenyl)-N5-(4- (trifluoromethyl)phenyl)- 6,7-dihydropyrazolo[1,5- a]pyrazine-3,5(4H)- dicarboxamide::US9598423, Example 242

SMILES Cc1cc(ccc1F)-c1nn2CCN(Cc2c1C(N)=O)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=MYCKMTJRHKLGAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302674   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302674(2-(4-Fluoro-3- methylphenyl)-N5-(4- (trifluorometh...)
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302674(2-(4-Fluoro-3- methylphenyl)-N5-(4- (trifluorometh...)
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent