BDBM303139 US10137202, Compound TAM558

SMILES CCCO[C@H](C[C@H](C(C)C)N(CCC)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C)[C@@H](C)CC)c1nc(cs1)C(=O)N[C@H](C[C@H](C)C(=O)NNC(=O)OCCOCCOCCOCCNC(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1)Cc1ccc(O)cc1

InChI Key InChIKey=GJSOQVVIEZWQBH-FOJMMPRNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303139   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303139(US10137202, Compound TAM558)
Affinity DataIC50:  98nMAssay Description:cell proliferation arrest on HT1080 cells (CPA; crystal violet).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303139(US10137202, Compound TAM558)
Affinity DataIC50:  1.90E+3nMAssay Description:TPI; Tubulin Polymerization assay kit; Cytoskeleton, Cat. #BK011P.More data for this Ligand-Target Pair
In DepthDetails US Patent