BDBM303190 US10137122, Compound 63
SMILES CC1(C)CC(=O)C2=C(C1)Nc1n[nH]c(c1C2c1cccc(F)c1C(F)(F)F)C(F)(F)F
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 303190
Affinity DataIC50: <100nMAssay Description:A solution of 4× inhibitor (5 μL), 4× substrate/ATP-Metal solution (5 μL), and 2× Kinase solution (10 μL) was prepared with assay buff...More data for this Ligand-Target Pair
Affinity DataKd: 2.76E+5nMAssay Description:Approximately 20,000 Response Units (RU) of anti GST-antibody (GE Healthcare Life Sciences) were immobilized on Flow Cell (FC) 1 and FC2 of a new, fr...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:20 μL/well of 4.7 nM GSK3β and 7 μM peptide in KBA (250 mM HEPES (pH 7.5), 50 mM MgCl2, 5 mM EGTA, 0.05% BRIJ-35) were dispensed onto ...More data for this Ligand-Target Pair