BDBM303538 US10138229, Example 49::US10875852, Example 49

SMILES CC#CC(=O)N1CCC(Cn2cc(C(N)=O)c(n2)-c2ccc(Oc3ccccc3)cc2)CC1

InChI Key InChIKey=DDCJCCFCJNXBNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303538   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303538(US10138229, Example 49 | US10875852, Example 49)
Affinity DataIC50:  180nMAssay Description:An HTRF assay (Cisbio KinEASE-TK cat #62TK0PEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303538(US10138229, Example 49 | US10875852, Example 49)
Affinity DataIC50:  180nMAssay Description:TBDAn HTRF assay (Cisbio KinEASE-TK cat #62TKOPEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent