BDBM303556 US10138229, Example 67::US10875852, Example 67

SMILES COc1ccc(Oc2ccc(cc2)-c2nn(cc2C(N)=O)[C@@H]2CCCN(C2)C(=O)C=C)cc1

InChI Key InChIKey=YOENBUNVMFFNHV-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303556   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303556(US10138229, Example 67 | US10875852, Example 67)
Affinity DataIC50:  38nMAssay Description:An HTRF assay (Cisbio KinEASE-TK cat #62TK0PEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303556(US10138229, Example 67 | US10875852, Example 67)
Affinity DataIC50:  38nMAssay Description:TBDAn HTRF assay (Cisbio KinEASE-TK cat #62TKOPEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent