BDBM303853 US10138241, Example 39::US11130754, Example 39

SMILES CN1CCN(CC1)S(=O)(=O)c1ccc2ncc(-n3cc(cn3)-c3cc(C(=O)NC4CC4)c(F)cc3C)n2c1

InChI Key InChIKey=SHKKQCAEAUCRIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303853   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303853(US10138241, Example 39 | US11130754, Example 39)
Affinity DataIC50:  4nMAssay Description:Method: In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303853(US10138241, Example 39 | US11130754, Example 39)
Affinity DataIC50:  4nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent