BDBM303898 US10138241, Example 85::US11130754, Example 85

SMILES COCCOc1ccn2c(cnc2c1)-n1cc(cn1)-c1cc(ccc1C)C(=O)NC1CC1

InChI Key InChIKey=KHWITQZALFAMGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303898   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303898(US10138241, Example 85 | US11130754, Example 85)
Affinity DataIC50:  3.90nMAssay Description:Method: In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303898(US10138241, Example 85 | US11130754, Example 85)
Affinity DataIC50:  3.90nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent