BDBM303964 US10138242, Compound 50

SMILES CC(C)c1ccc(CN2CCc3c(C2)c(nn3CCO)C(=O)NCc2cccc3ccccc23)cc1

InChI Key InChIKey=BCECVSNTMDSAOI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 303964   

TargetPEX5-related protein/Peroxisomal membrane protein PEX14(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM303964(US10138242, Compound 50)
Affinity DataEC50:  2.89E+4nMAssay Description:The assay uses two types of beads: donor beads are coupled with streptavidin, and acceptor beads are coupled with an anti His-tag antibody. Upon exci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeroxisomal membrane protein PEX14(Homo sapiens (Human))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM303964(US10138242, Compound 50)
Affinity DataEC50:  1.49E+5nMAssay Description:Inhibition of biotinylated PEX5-derived ALSENWAQEFLA binding to human N-terminal His-tagged PEX14 (21 to 84 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPEX5-related protein/Peroxisomal membrane protein PEX14(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM303964(US10138242, Compound 50)
Affinity DataIC50:  2.89E+3nMAssay Description:Antitrypanosomal activity was tested on T. brucei brucei bloodstream from parasites (strainżLister 427, VATMITat 1.2). Stock solutions of compounds (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent