BDBM304128 USRE47141, Example 48

SMILES COCc1ccccc1NCc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1

InChI Key InChIKey=SHDMIJPWBFJPGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304128   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Ewha University—Industry Collaboration Foundation

US Patent
LigandPNGBDBM304128(USRE47141, Example 48)
Affinity DataIC50:  24.1nMAssay Description:ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent