BDBM304359 (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(5-(trifluoromethyl)pyridin-2-yl)piperazine::US10144715, Compound 7-35

SMILES CC(C)[C@@H]1CN(CCN1c1ccc(cn1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=LOLXQIJKVFWHMU-SFHVURJKSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304359   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304359((R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(5-...)
Affinity DataEC50:  4nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304359((R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(5-...)
Affinity DataEC50:  13nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent