BDBM304911 3-(4-Cyano-2-methylphenyl)- 3-(3-((7-fluoro-4-methyl-1,1- dioxido-4,5-dihydrobenzo[f] [1,2]thiazepin-2(3H)-yl) methyl)-4-methylphenyl) propanoic acid::US10144731, Example 215

SMILES CC1CN(Cc2cc(ccc2C)C(CC(O)=O)c2ccc(cc2C)C#N)S(=O)(=O)c2ccc(F)cc2C1

InChI Key InChIKey=HBNAUONLWDFYEA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304911   

TargetKelch-like ECH-associated protein 1 [321-609](Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM304911(3-(4-Cyano-2-methylphenyl)- 3-(3-((7-fluoro-4-meth...)
Affinity DataIC50:  55nMAssay Description:100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM304911(3-(4-Cyano-2-methylphenyl)- 3-(3-((7-fluoro-4-meth...)
Affinity DataEC50:  55nMAssay Description:NAD(P)H:quinone oxidoreductase 1 (NQO1), also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent