BDBM30542 5,6-Dihydro-1H-pyridin-2-one, 4an

SMILES [H][C@]12CCC[C@@]1([H])C(=O)C(C(=O)N2Cc1ccc(F)c(C)c1)C1=Nc2ccc(NS(C)(=O)=O)cc2S(=O)(=O)N1

InChI Key InChIKey=NDDHGYSHOLFFTA-NTEFNCDNSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30542   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Anadys Pharmaceuticals

LigandPNGBDBM30542(5,6-Dihydro-1H-pyridin-2-one, 4an)
Affinity DataIC50:  28nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme (NS5B H77 1a), RNA substrate, and [alpha-33P]GTP/GTP with inhibitor c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Anadys Pharmaceuticals

LigandPNGBDBM30542(5,6-Dihydro-1H-pyridin-2-one, 4an)
Affinity DataIC50: <10nM EC50:  34nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed