BDBM306186 US10144742, Compound I-348

SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1COC1)C(=O)NCCCc1ncc[nH]1

InChI Key InChIKey=SMXJTYSAEWSGGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306186   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM306186(US10144742, Compound I-348)
Affinity DataIC50: <100nMAssay Description:To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent