BDBM306777 N-(2-((5- ((1R,3R)-2- (2,2- difluoroethyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 4-methyl- pyridin-2- yl)oxy)ethyl)- 3-fluoro- propan-1-amine::US10149839, Example 63
SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)F)c1cnc(OCCNCCCF)cc1C
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 306777
Affinity DataIC50: 1.80nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair