BDBM307953 N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-pyrrolo[3,2-b]pyridin-6-yl]pyridin-2-yl}-6-azaspiro[3.4]octan-2-amine::US9650358, Example 249

SMILES Fc1cccc(Cn2ccc3ncc(cc23)-c2cc(NC3CC4(C3)CCNC4)ncc2Cl)c1

InChI Key InChIKey=SRNNKTBFJNJOIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307953   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM307953(N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-pyrrolo[3,2-b...)
Affinity DataIC50:  25nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent