BDBM309430 (2R,3aS,4R,9bS)-12-(cyclopropylmethyl)- N-(3,4-dichlorobenzyl)-3a,8-dihydroxy- 1,2,3,3a,4,5-hexahydro-4,9b-(epimino- ethano)cyclopenta[a]naphthalene-2- carboxamide::US9656962, Compound 46

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@H](C[C@@]34O)C(=O)NCc3ccc(Cl)c(Cl)c3)c2c1

InChI Key InChIKey=CVTHHKMXXKHSLK-XVRHYUDRSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309430   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM309430((2R,3aS,4R,9bS)-12-(cyclopropylmethyl)- N-(3,4-dic...)
Affinity DataEC50:  0.200nMAssay Description:Radioligand binding assays (screening and dose-displacement) use 0.1 nM [3H]-nociceptin (Perkin Elmer, Shelton, Conn.; 87.7 Ci/mmole) with 12 μg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM309430((2R,3aS,4R,9bS)-12-(cyclopropylmethyl)- N-(3,4-dic...)
Affinity DataEC50: >2.00E+4nMAssay Description:δ-Opioid Receptor Binding Assay Procedures: δ-Opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displace...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent