BDBM309830 (R)-3-(4-(1-cyclopentylpiperidin-4-yl)phenylamino)-5-(3-(cyclopropanecarboxamido)piperidin-1-yl)pyrazine-2-carboxamide::US9656988, Example 299
SMILES NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(CC1)C1CCCC1)N1CCC[C@H](C1)NC(=O)C1CC1
InChI Key InChIKey=AYPQJCUSHCNNTD-XMMPIXPASA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 309830
Affinity DataIC50: <10nMAssay Description:Human Btk kinase (Genbank accession # NP_000052) was purified from insect cells as a full-length construct containing a N-terminal 6×-His tag. Btk ki...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Human Btk kinase (Genbank accession # NP_000052) was purified from insect cells as a full-length construct containing a N-terminal 6×-His tag. Btk ki...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The degree of inhibition of a panel of kinases is determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate subst...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:The degree of inhibition of a panel of kinases is determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate subst...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The degree of inhibition of a panel of kinases is determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The degree of inhibition of a panel of kinases is determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate subst...More data for this Ligand-Target Pair