BDBM310096 US10377768, Compound 10::US9657033, Compound 10

SMILES Fc1cccc(Cl)c1C(=O)Nc1cc2n(ncc2cn1)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=JXWGGOBERMHMAL-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 310096   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310096(US10377768, Compound 10 | US9657033, Compound 10)
Affinity DataEC50:  3.63E+3nMAssay Description:Recombinant,HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310096(US10377768, Compound 10 | US9657033, Compound 10)
Affinity DataEC50:  4.33E+3nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310096(US10377768, Compound 10 | US9657033, Compound 10)
Affinity DataEC50:  3.63E+3nMAssay Description:Recombinant, HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310096(US10377768, Compound 10 | US9657033, Compound 10)
Affinity DataEC50:  4.33E+3nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent