BDBM310097 US10377768, Compound 11::US9657033, Compound 11

SMILES Cc1nn(cc1S(=O)(=O)n1ncc2cnc(NC(=O)c3c(F)cccc3Cl)cc12)C(F)F

InChI Key InChIKey=FYSJQUKSXFKHCF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 310097   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310097(US10377768, Compound 11 | US9657033, Compound 11)
Affinity DataEC50:  447nMAssay Description:Recombinant,HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310097(US10377768, Compound 11 | US9657033, Compound 11)
Affinity DataEC50:  324nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310097(US10377768, Compound 11 | US9657033, Compound 11)
Affinity DataEC50:  447nMAssay Description:Recombinant, HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310097(US10377768, Compound 11 | US9657033, Compound 11)
Affinity DataEC50:  324nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent