BDBM310179 (S)-N-((R)-5-((1-(difluoromethyl)-3-methyl-1H-pyrazol-4-yl)sulfonyl)-7-(hydroxymethyl)-5,6,7,8-tetrahydro-1,5-naphthyridin-3-yl)-2,3,3-trimethylbutanamide ::US10377768, Compound 92::US9657033, Compound 92

SMILES C[C@H](C(=O)Nc1cnc2C[C@@H](CO)CN(c2c1)S(=O)(=O)c1cn(nc1C)C(F)F)C(C)(C)C

InChI Key InChIKey=YHSYFKUIXIFNDB-TZMCWYRMSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310179   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310179((S)-N-((R)-5-((1-(difluoromethyl)-3-methyl-1H-pyra...)
Affinity DataEC50:  1.00E+4nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM310179((S)-N-((R)-5-((1-(difluoromethyl)-3-methyl-1H-pyra...)
Affinity DataEC50:  1.00E+4nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent