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BDBM31062 5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide::5-methyl-N-(5-quinolyl)thiophene-2-sulfonamide::5-methyl-N-quinolin-5-yl-thiophene-2-sulfonamide::5-methyl-N-quinolin-5-ylthiophene-2-sulfonamide::MLS000060442::SMR000067302::cid_2082098

SMILES: Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12

InChI Key: InChIKey=XSYLVTQRXJCUTP-UHFFFAOYSA-N

Data: 7 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 31062   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hsf1 protein


(Mus musculus)
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/an/an/a 3.91E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2P55KXK
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/an/an/a 9.62E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2251GJ9
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/an/an/a 2.76E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2ZC817P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor


(Homo sapiens (Human))
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/an/an/a>9.51E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q25X2795
More data for this
Ligand-Target Pair
Nuclear receptor ROR-alpha


(Homo sapiens)
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/a 6.89E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q26Q1VNZ
More data for this
Ligand-Target Pair
Steroidogenic Factor 1


(Homo sapiens (human))
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/a 5.75E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2319T8T
More data for this
Ligand-Target Pair
Steroidogenic Factor 1


(Homo sapiens (human))
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/a 5.33E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2PR7TCX
More data for this
Ligand-Target Pair
Nuclear receptor ROR-alpha


(Homo sapiens)
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/a 4.03E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2TH8K3N
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens)
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/a 2.91E+3n/an/an/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2KH0KNM
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (human))
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/a 1.10E+3n/an/an/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2S46Q8P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM31062
PNG
(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Show SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12
Show InChI InChI=1S/C14H12N2O2S2/c1-10-7-8-14(19-10)20(17,18)16-13-6-2-5-12-11(13)4-3-9-15-12/h2-9,16H,1H3
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n/an/a>3.90E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
External Assay ID: S1P3_IC50_CS_5H1E_Antagonists Name: S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2D50KC1
More data for this
Ligand-Target Pair