BDBM310652 ((S)-4,4-Difluoro-2-methylpyrrolidin-1-yl)(2-((3R,5S)-3,5-dihydroxypiperidine-1-carbonyl)-5-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-(trifluoromethoxy)phenyl)thiazol-4-yl)methanone::US10150762, Example 9
SMILES C[C@H]1CC(F)(F)CN1C(=O)c1nc(sc1-c1ccc(cc1OC(F)(F)F)C(O)(C(F)(F)F)C(F)(F)F)C(=O)N1C[C@@H](O)C[C@@H](O)C1
InChI Key InChIKey=VYJNXVXYSQKVHX-WCFLWFBJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 310652
Affinity DataIC50: 10nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Affinity DataKd: 0.0700nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair