BDBM310757 US10150764, Compound 42

SMILES CCN([C@@H]1COC[C@H]1OC)c1cc(Cl)cc(C(=O)NCc2c(C)[nH]n(C)c2=O)c1C

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310757   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM310757(US10150764, Compound 42)
Affinity DataIC50: >5.00E+4nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent