BDBM311149 (S)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-methyl-1H-indazol- 4-yl)oxy)phenyl)picolinamide::US10155752, Compound 39::US9834543, Compound 39

SMILES Cn1ncc2c(Oc3ccc(cc3)-c3cc(cc(n3)C(N)=O)[C@H](O)CO)ccc(F)c12

InChI Key InChIKey=ZAVQNBXALRKXSF-LJQANCHMSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 311149   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM311149((S)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-meth...)
Affinity DataKi:  470nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM311149((S)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-meth...)
Affinity DataKi:  470nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM311149((S)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-meth...)
Affinity DataIC50:  797nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM311149((S)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-meth...)
Affinity DataIC50:  797nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent