BDBM311149 (S)-4-(1,2-dihydroxyethyl)-6-(4- ((7-fluoro-1-methyl-1H-indazol- 4-yl)oxy)phenyl)picolinamide::US10155752, Compound 39::US9834543, Compound 39
SMILES Cn1ncc2c(Oc3ccc(cc3)-c3cc(cc(n3)C(N)=O)[C@H](O)CO)ccc(F)c12
InChI Key InChIKey=ZAVQNBXALRKXSF-LJQANCHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 311149
Affinity DataKi: 470nMAssay Description:The hNav1.7 expressing HEK-293 cells are plated on 35 mm culture dishes pre-coated with poly-D-lysine in standard DMEM culture media (Mediatech, Inc....More data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Affinity DataIC50: 797nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
Affinity DataIC50: 797nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair