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BDBM311160 (S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-chlorophenyl)pyridin-2-yl)acetamide::US10155760, Example 8

SMILES: CC(C)C[C@@H](COc1ccc(Br)cc1Cl)NC(=O)OC(C)(C)C

InChI Key: InChIKey=YNPPHGUKSUNNMF-ZDUSSCGKSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311160   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1


(Homo sapiens)
BDBM311160
PNG
((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-chloro...)
Show SMILES CC(C)C[C@@H](COc1ccc(Br)cc1Cl)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C17H25BrClNO3/c1-11(2)8-13(20-16(21)23-17(3,4)5)10-22-15-7-6-12(18)9-14(15)19/h6-7,9,11,13H,8,10H2,1-5H3,(H,20,21)/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
US Patent
n/an/a 0.530n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US10155760 (2018)

More data for this
Ligand-Target Pair