BDBM31141 1H-pyrrolo[2,3-f]quinoline-3-carboxylate, 20

SMILES CCOC(=O)c1c(Cc2cccc(Cl)c2)[nH]c2c1cc(O)c1ncccc21

InChI Key InChIKey=ATYAIAPLYDCLHM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31141   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich Alexander University Erlangen

LigandPNGBDBM31141(1H-pyrrolo[2,3-f]quinoline-3-carboxylate, 20)
Affinity DataIC50:  580nM EC50:  4.30E+3nMAssay Description:For determination of the activity of 5-LO in 40000g supernatant (S40), aliquots of the supernatants were added to reaction mix, and were preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed