BDBM311520 5-{[cis-2- aminocyclohexyl]amino}- N-(3-carbamoyl-1- pyridin-3-yl-1H- pyrazol-4- yl)pyrazolo[1,5- a]pyrimidine-3- carboxamide::US10155765, Example 6

SMILES N[C@@H]1CCCC[C@@H]1Nc1ccn2ncc(C(=O)Nc3cn(nc3C(N)=O)-c3cccnc3)c2n1

InChI Key InChIKey=TYFNEYCNSDXOTM-CVEARBPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311520   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311520(5-{[cis-2- aminocyclohexyl]amino}- N-(3-carbamoyl-...)
Affinity DataIC50:  0.800nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent