BDBM311522 5-{[trans-2- aminocyclohexyl]amino}- N-(3-carbamoyl-1- methyl-1H-pyrazol-4- yl)pyrazolo[1,5- a]pyrimidine-3- carboxamide trifluoroacetate::US10155765, Example 8

SMILES Cn1cc(NC(=O)c2cnn3ccc(N[C@@H]4CCCC[C@H]4N)nc23)c(n1)C(N)=O

InChI Key InChIKey=SSMUXZNGWKTWKM-VXGBXAGGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311522   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311522(5-{[trans-2- aminocyclohexyl]amino}- N-(3-carbamoy...)
Affinity DataIC50:  20nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent