BDBM311566 2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[1-methyl-3- (methylcarbamoyl)- 1H-pyrazol-4- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10155765, Example 64

SMILES CNC(=O)c1nn(C)cc1NC(=O)c1ccc2cnc(N[C@@H]3CCCC[C@@H]3N)nn12

InChI Key InChIKey=KYAYJFNEGQKFFM-QWHCGFSZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311566   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311566(2-{[(1R,2S)-2- aminocyclohexyl]amino}- N-[1-methyl...)
Affinity DataIC50:  13nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent