BDBM311841 8-(7-Chloro-1H-indazol-5-yl)-7-cyclopropyl-5-methyl-2-trifluoromethyl)imidazo[1,2-c]pyrimidine::US10155769, Example 79

SMILES Cc1nc(C2CC2)c(-c2cc(Cl)c3[nH]ncc3c2)c2nc(cn12)C(F)(F)F

InChI Key InChIKey=CJEQVSUBYGYUQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311841   

TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311841(8-(7-Chloro-1H-indazol-5-yl)-7-cyclopropyl-5-methy...)
Affinity DataIC50:  1.26nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent