BDBM311875 US10166214, Example 11::US10675268, Example 11::US9789082, Example 11

SMILES CC(C)(NC(=O)[C@@H]1[C@H]2CNC[C@@H]12)c1nc2ccc(Cl)cc2[nH]1

InChI Key

Data  15 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 311875   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi:  106nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi:  106nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi:  106nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >8.58E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >8.58E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >8.58E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >8.91E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >8.91E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >8.91E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >9.59E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >9.59E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >9.59E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >9.85E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >9.85E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataKi: >9.85E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataEC50:  8.10nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM311875(US10166214, Example 11 | US10675268, Example 11 | ...)
Affinity DataEC50:  8.10nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent