BDBM31201 spiro-oxindole, 7

SMILES CN(C)C(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@@]2([C@H]1c1cc(F)cc(Cl)c1)C(=O)Nc1cc(Cl)ccc21

InChI Key InChIKey=FHATUCFTBPTWGI-QDMVCWPOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31201   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

LigandPNGBDBM31201(spiro-oxindole, 7)
Affinity DataKi:  44nM ΔG°:  -9.96kcal/molepH: 7.5 T: 2°CAssay Description:The dose-dependent binding experiments were carried out with serial dilutions of the tested compounds in DMSO. A 5 ul sample of the tested samples an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed