BDBM31203 spiro-oxindole, 9

SMILES CC(C)(C)C[C@@H]1N[C@@H]([C@@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCN1CCOCC1

InChI Key InChIKey=YTBYOWZWBDYLQF-MHGRFWDASA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31203   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

LigandPNGBDBM31203(spiro-oxindole, 9)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.31kcal/molepH: 7.5 T: 2°CAssay Description:The dose-dependent binding experiments were carried out with serial dilutions of the tested compounds in DMSO. A 5 ul sample of the tested samples an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed