BDBM312139 2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinylisoquinolin-1(2H)-one::US9604931, 15c::US9623021, Compound 15c
SMILES Oc1cc(O)c2c(c1)c(C=C)cn(-c1ccc(O)c(F)c1)c2=O
InChI Key InChIKey=UZCGSEMPWJYIKG-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 312139
Affinity DataKi: 3.96nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 3.96nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Affinity DataKi: 205nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Affinity DataKi: 205nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair