BDBM31222 2-phenoxybenzoyltryptophan derivative, R4C4

SMILES OC(=O)[C@H](Cc1cn(Cc2ccc(OCc3ccccc3)cc2)c2ccc(cc12)C#N)NC(=O)c1ccccc1Oc1ccccc1

InChI Key InChIKey=AOWLHPAIWPBAAQ-DHUJRADRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31222   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31222(2-phenoxybenzoyltryptophan derivative, R4C4)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.12kcal/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed